Emory University’s Laboratory of Biochemical Pharmacology (LOBP), Department of Pediatrics is actively recruiting a PhD Molecular Modeler with chemistry and/or biochemistry experience to join our drug discovery group. Our multidisciplinary antiviral research program is composed of a broad team of virologists, molecular biologists, medicinal chemists and pharmacologists with a collective research focus on the development of antiviral agents for the treatment and eradication of infections caused by human immunodeficiency viruses (HIV), hepatitis viruses (including hepatitis B and C), herpesviruses, influenza, dengue, ebola, chikungunya, cytomegalovirus (CMV), respiratory syncytial virus (RSV), and other emerging viruses. Our group also targets cancers and viral proteins of importance to humans.
As a Molecular Modeler, you will apply computational methods, including structure-based drug design, homology modeling, QSAR, cheminformatics, ligand/receptor docking, high-throughput virtual screening (HTVS), molecular dynamics, quantum methods, diversity/similarity analysis and machine learning/artificial intelligence (ML/AI) to the design of molecules and question libraries to advance various drug discovery projects. You will participate with multi-disciplinary teams providing key expertise in the use and interpretation of structural data related to drug targets, their endogenous ligands, agonists and/or antagonists.
Your responsibilities will include:
- Concise execution and clear communication of computational experiments and structural information to team members to facilitate the discovery of new drugs.
- Development of novel computational methods to address key drug discovery questions.
- Perform some biochemical studies to evaluate the computational hits identified for activity.
- Initiate novel science that is worthy of both external funding and publication in peer reviewed journals.
- Write abstracts, papers and grants
- Maintain a good code of ethics
- PhD in chemistry or computational science or related discipline is required.
- Experience working with multi-disciplinary teams
- Familiarity with one or more standard computational chemistry packages (such as Maestro/Schrödinger, MOE/Chemical Computing Group and/or OpenEye tools).
- Experience in the application of computational chemistry tools to drug discovery.
- Experience with cheminformatics toolkits and packages (e.g., Schrödinger, MOE, KNIME ChemAxon, CambridgeSoft)
- Expertise in large scale data handling (ie. extraction, manipulation, and merging multiple data sources with tools, such as Pipeline Pilot).
- Experience with high-throughput virtual screening (HTVS), and/or machine learning/artificial intelligence (ML/AI).
- Excellent writing and verbal skills
- High motivation and drive
- Must be able to provide documentation of authorization to legally work in the United States.
Applications must include:
Cover letter describing your relevant experience
Complete contact information for three professional references
Applications will be considered starting immediately, on a rolling basis, and open until filled.
Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribute to the diversity and excellence of our academic community.
Emory University is an equal employment opportunity and affirmative action employer. Women, minorities, people with disabilities and veterans are strongly encouraged to apply.