The Laboratory of Biochemical Pharmacology (LOBP), Emory University School of Medicine in Atlanta, Georgia, USA, directed by Dr. Raymond F. Schinazi, is a multidisciplinary research group with expertise in medicinal chemistry, virology, molecular biology, toxicology, pharmacology, immunology, structural biology, and computational biology. The Schinazi group focuses on the discovery and development of novel antiviral agents and has contributed to drug discovery for HIV, herpesviruses, hepatitis B and C, SARS-CoV-2, and emerging viruses including dengue, West Nile, yellow fever, EBV, chikungunya, norovirus, and enteroviruses. The group has more than 60 researchers and staff. Its well-established synthetic and medicinal chemistry group has its own 400 MHz NMR, UPLC/MS, preparative HPLC, automated purification systems, microwave synthesis reactor, and other modern equipment supporting compound design, multi-step synthesis, purification, and structural characterization.
Position
LOBP is seeking a highly motivated Postdoctoral Fellow with expertise in synthetic organic and medicinal chemistry to join its chemistry group. The successful candidate will contribute to the design, synthesis, and optimization of novel nucleoside analogs and small molecules as potential antiviral agents. The appointment is for a maximum of three years with yearly renewal based on satisfactory research progress and availability of funding. Postdoctoral appointments may not exceed five years.
Responsibilities
• Design and execute multi-step syntheses of complex small molecules, including nucleoside analogs, heterocyclic compounds, and peptide-based antiviral agents.
• Independently plan synthetic routes, troubleshoot reactions, and optimize reaction conditions.
• Purify and characterize compounds using 1D/2D NMR, MS, HPLC/UPLC, chromatography, and related techniques.
• Analyze and interpret experimental results and maintain accurate research records.
• Review scientific literature and remain current with developments in synthetic and medicinal chemistry.
• Collaborate with multidisciplinary research teams.
• Prepare manuscripts, abstracts, and scientific presentations; assist in grant writing, and regularly present research findings.
• Maintain high standards of laboratory safety, scientific integrity, professionalism, and confidentiality.
JOB DESCRIPTION:
MINIMUM QUALIFICATIONS:
PREFERRED QUALIFICATIONS:
NOTE: Position tasks are required to be performed in-person at an Emory University location; working remote is not an option. Emory reserves the right to change this status with notice to employee.
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