The Handler Laboratory at Emory University School of Medicine, led by Dr. Jesse Handler, is seeking a
passionate and driven Postdoctoral Fellow to join our founding team. Our lab is dedicated to uncovering
the molecular and evolutionary mechanisms that drive pancreatic and colorectal cancer metastasis and
drug resistance — and to translating these discoveries into new therapies and diagnostics. We employ
cutting-edge approaches in genome engineering, synthetic biology, genomics, and computational
biology to illuminate the regulatory networks governing neoplastic cells and tissues.
The Postdoctoral Fellow will lead innovative projects that integrate wet-lab and dry-lab technologies.
Fellows will be encouraged to develop independent lines of inquiry within the lab’s mission while also
contributing to collaborative, team-based efforts. We are seeking a scientist whose curiosity, creativity,
and passion inspire them to pursue ambitious scientific directions through bold approaches with the
potential for transformative impact.
The Handler Lab uncovers mechanistic insights primarily through genetic manipulation (e.g., DNA
barcodes, CRISPRKO/a/i, shRNAs) coupled with epigenomic readouts in cancer models. Findings from
the lab are validated using patient-derived data, which in turn guides the design of further
experimentation — establishing a “bench-to-bedside-to-bench” research cycle that fuels discovery and
innovation.
As one of the first postdoctoral fellows in the Handler Lab, you will play a central role in shaping both
the lab’s scientific direction and its culture. Dr. Handler is deeply committed to the success of trainees
and will provide close mentorship to support your career development. Fellows can expect: weekly one-on-one mentorship meetings with Dr. Handler; close collaboration within an interdisciplinary, highenergy team; opportunities for first-author publications in high-impact journals; the chance to present
your work at seminars and national meetings; inventorship opportunities on patents; experience writing
and contributing to fellowship and grant applications; and tailored support for building an independent
research program and preparing for the next stage of your career (e.g., academic faculty, industry
leadership, or other preferred career trajectories). Our team operates as a highly functional and
collaborative unit, with each member taking ownership of their specific roles. Together, we strive to
bridge the gap between mechanistic research and patient care.
JOB DESCRIPTION:
MINIMUM QUALIFICATIONS:
NOTE: Position tasks are required to be performed in-person at an Emory University location; working remote is not an option. Emory reserves the right to change this status with notice to employee.
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